Comment on the intravenous tranexamic acid use in revision total joint arthroplasty
نویسندگان
چکیده
منابع مشابه
Tranexamic Acid in Total Joint Arthroplasty: Efficacy and Safety
Despite improvements in surgical and anesthetic techniques, total joint arthroplasty (TJA) is still associated with substantial blood loss and postoperative anemia (1). A considerable portion of patients with postoperative anemia require blood transfusion, which has been shown to negatively affect the outcome of TJA and predisposes patients to development of surgical site infection and peripr...
متن کاملTranexamic acid in total joint arthroplasty.
Total Joint Arthroplasty (TJA) is one of the most common orthopaedic procedures performed worldwide that restores function and allows patients to maintain their activities of daily living [1] Optimizing patients for surgery is of utmost importance, including conserving blood to minimize the risk of surgical site infection since immunomodulatory effects of allogenic blood [2] predisposes TJA pat...
متن کاملIs combined topical and intravenous tranexamic acid superior to single use of tranexamic acid in total joint arthroplasty?
BACKGROUND To compare the efficacy and safety of the combined application of both intravenous and topical tranexamic acid (TXA) versus the single use of either application in patients with total knee and hip arthroplasty (TKA and THA). METHODS Potentially relevant studies were identified from electronic databases including Medline, PubMed, Embase, ScienceDirect, and the Cochrane Library. Rand...
متن کاملtranexamic acid in total joint arthroplasty: efficacy and safety
despite improvements in surgical and anesthetic techniques, total joint arthroplasty (tja) is still associated with substantial blood loss and postoperative anemia (1). a considerable portion of patients with postoperative anemia require blood transfusion, which has been shown to negatively affect the outcome of tja and predisposes patients to development of surgical site infection and peripros...
متن کاملEffectiveness of tranexamic acid in revision total knee arthroplasty.
The effectiveness of Tranexamic Acid (TXA, antifibrinolytic drug) in reducing allogeneic blood transfusion requirements has not been tested in revision total knee arthroplasty. The aim of this study was to assess the effectiveness of TXA after two intravenous doses of 1 g each. Between April 2006 and February 2010, 68 consecutive patients (19 male, 49 female) of 74 +/- 6 [m +/- SD] years of age...
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ژورنال
عنوان ژورنال: Drug Design, Development and Therapy
سال: 2018
ISSN: 1177-8881
DOI: 10.2147/dddt.s188844